Which supplement works better to decrease fatigue: choline citrate or tryptophan?
Ratings at a Glance
| Supplement | Effectiveness Rating | Confidence Rating |
|---|---|---|
| Choline Citrate | ![]() ![]() ![]() |
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| Tryptophan | ![]() ![]() ![]() |
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Effectiveness Rating: Choline Citrate vs Tryptophan
The effectiveness rating is a measure of the supplements' ability to decrease fatigue. This rating answers the question of whether or not a supplement does what it claims. The evidence shows tryptophan is better than choline citrate in its ability to decrease fatigue. Tryptophan should provide some positive results while choline citrate will not.
Confidence Rating: Choline Citrate vs Tryptophan
Another factor to take into account when comparing supplements is the confidence rating. This rating is a measure of how valid each supplement's effectiveness rating is. Remember, the confidence rating is a measure of how much you can trust the effectiveness rating. This rating is based on how many studies are included in the database on a supplement's claims. Ideally, you want a high effectiveness AND confidence rating.
Both choline citrate and tryptophan have low confidence ratings. This means neither supplement has an adequate amount of research to back up this claim. A low confidence rating questions the validity of the effectiveness rating.


