Which supplement works better to reduce joint pain: glucosamine sulfate or methylsulfonylmethane (msm)?

Ratings at a Glance

Supplement	Effectiveness Rating	Confidence Rating
Glucosamine Sulfate
Methylsulfonylmethane (MSM)

Effectiveness Rating: Glucosamine Sulfate vs Methylsulfonylmethane (MSM)

The effectiveness rating is a measure of the supplements' ability to reduce joint pain. This rating answers the question of whether or not a supplement does what it claims. Both glucosamine sulfate and methylsulfonylmethane (msm) have good (but not great) evidence showing they may be able to reduce joint pain. Both supplements should provide some positive results.

Confidence Rating: Glucosamine Sulfate vs Methylsulfonylmethane (MSM)

Another factor to take into account when comparing supplements is the confidence rating. This rating is a measure of how valid each supplement's effectiveness rating is. Remember, the confidence rating is a measure of how much you can trust the effectiveness rating. This rating is based on how many studies are included in the database on a supplement's claims. Ideally, you want a high effectiveness AND confidence rating.

Glucosamine Sulfate's confidence rating is higher than methylsulfonylmethane (msm)'s. This means glucosamine sulfate's effectiveness rating from above is more valid. This does not necessarily mean that glucosamine sulfate works better, it simply means the evidence (included in this database) backing up glucosamine sulfate is more established.