Methylsulfonylmethane (MSM)

Does methylsulfonylmethane (msm) work?

Overall Effectiveness Rating for Methylsulfonylmethane (MSM)

The overall effectiveness rating for methylsulfonylmethane (msm) is 2 out of 3. This rating means there is some evidence that using methylsulfonylmethane (msm) may lead to positive results. This rating also means that some evidence does not back up all claims. Below you can find individual ratings for specific claims.

Overall Confidence Rating for Methylsulfonylmethane (MSM)

There are 2 studies in the database on methylsulfonylmethane (msm); the confidence rating is 27. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for methylsulfonylmethane (msm) as a whole. There are also individual ratings for the claims below.

Products Containing Methylsulfonylmethane (MSM)

Products Containing Methylsulfonylmethane (MSM)
Proven Joint
Super Flexy
MILLECOR Joint Support
Core Flex
Full list of all 4 products containing Methylsulfonylmethane (MSM).

Individual Claims

The overall ratings above do no necessarily reflect each claim about methylsulfonylmethane (msm). Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Recovery Claims Effectiveness Rating Confidence Rating
reduce muscle damage
reduce muscle soreness
reduce joint pain


Title of Study
Effect of methylsulfonylmethane supplementation on exercise - Induced muscle damage and total antioxidant capacity
Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial