Which supplement works better to increase protein synthesis: arachidonic acid or leucine?

Ratings at a Glance

Supplement	Effectiveness Rating	Confidence Rating
Arachidonic Acid
Leucine

Effectiveness Rating: Arachidonic Acid vs Leucine

The effectiveness rating is a measure of the supplements' ability to increase protein synthesis. This rating answers the question of whether or not a supplement does what it claims. Both arachidonic acid and leucine have good (but not great) evidence showing they may be able to increase protein synthesis. Both supplements should provide some positive results.

Confidence Rating: Arachidonic Acid vs Leucine

Another factor to take into account when comparing supplements is the confidence rating. This rating is a measure of how valid each supplement's effectiveness rating is. Remember, the confidence rating is a measure of how much you can trust the effectiveness rating. This rating is based on how many studies are included in the database on a supplement's claims. Ideally, you want a high effectiveness AND confidence rating.

Leucine's confidence rating is higher than arachidonic acid's. This means leucine's effectiveness rating from above is more valid. This does not necessarily mean that leucine works better, it simply means the evidence (included in this database) backing up leucine is more established.