Does phosphatidylserine work?

Overall Effectiveness Rating for Phosphatidylserine

The overall effectiveness rating for phosphatidylserine is 1.6 out of 3. This rating means there is some evidence that using phosphatidylserine may lead to positive results. This rating also means that some evidence does not back up all claims. Below you can find individual ratings for specific claims.

Overall Confidence Rating for Phosphatidylserine

There are 10 studies in the database on phosphatidylserine; the confidence rating is 35. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for phosphatidylserine as a whole. There are also individual ratings for the claims below.

Products Containing Phosphatidylserine

Products Containing Phosphatidylserine
Genius Consciousness
GG Energy
Jocko Discipline Go
Procera Advanced Brain
Ai Mode Brain Booster
Full list of all 8 products containing Phosphatidylserine.

Individual Claims

The overall ratings above do no necessarily reflect each claim about phosphatidylserine. Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Body Composition (weight, muscle, body fat) Claims Effectiveness Rating Confidence Rating
increase fat burning

Performance Claims Effectiveness Rating Confidence Rating
improve cycling performance
improve sports performance
improve sprint performance
decrease fatigue

Hormone Function Claims Effectiveness Rating Confidence Rating
decrease cortisol levels
increase levels of growth hormone
increase testosterone

Cardiovascular Health Claims Effectiveness Rating Confidence Rating
lower blood pressure

Recovery Claims Effectiveness Rating Confidence Rating
reduce muscle damage
reduce muscle soreness

Mental Health Claims Effectiveness Rating Confidence Rating
improve cognitive ability
improve memory
improve mood
decrease stress


Title of Study
Effects of phosphatidylserine on exercise capacity during cycling in active males
Effects of phosphatidylserine on oxidative stress following intermittent running
Effects of Soy Lecithin Phosphatidic Acid and Phosphatidylserine Complex (PAS) on the Endocrine and Psychological Responses to Mental Stress
Phosphatidylserine supplementation and recovery following downhill running
Soybean-Derived Phosphatidylserine Improves Memory Function of the Elderly Japanese Subjects with Memory Complaints
The effect of phosphatidylserine on golf performance
The effects of IQPLUS Focus on cognitive function, mood and endocrine response before and following acute exercise
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
The Influence of Phosphatidylserine Supplementation on Mood and Heart Rate when Faced with an Acute Stressor
The Influence of Soy-derived Phosphatidylserine on Cognition in Age-Associated Memory Impairment