Do multivitamins work?


Overall Effectiveness Rating for Multivitamins

The overall effectiveness rating for multivitamins is 1.9 out of 3. This rating means there is some evidence that using multivitamins may lead to positive results. This rating also means that some evidence does not back up all claims. Below you can find individual ratings for specific claims.

Overall Confidence Rating for Multivitamins

There are 15 studies in the database on multivitamins; the confidence rating is 40. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for multivitamins as a whole. There are also individual ratings for the claims below.

Individual Claims

The overall ratings above do no necessarily reflect each claim about multivitamins. Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Performance Claims Effectiveness Rating Confidence Rating
improve cardiovascular endurance
improve running performance
decrease fatigue
increase strength
improve cycling sprint performance
increase alertness

Immune Health Claims Effectiveness Rating Confidence Rating
improve immune function

Recovery Claims Effectiveness Rating Confidence Rating
improve recovery
reduce muscle damage

Mental Health Claims Effectiveness Rating Confidence Rating
improve cognitive ability
improve memory
increase concentration
improve mood
decrease stress


Title of Study
Antioxidants do not prevent postexercise peroxidation and may delay muscle recovery
Can a short period of micronutrient supplementation in older institutionalized people improve response to influenza vaccine? A randomized, controlled trial
Chronic multivitamin-mineral supplementation does not enhance physical performance
Effect of A Liquid Multivitamin/Mineral Supplement on Anaerobic Exercise Performance
Effect of a multivitamin and mineral supplement on infection and quality of life. A randomized, double-blind, placebo-controlled trial
Effect of daily vitamin E and multivitamin-mineral supplementation on acute respiratory tract infections in elderly persons: a randomized controlled trial
Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: a randomised controlled trial
Effects of a multivitamin/multimineral supplement on young males with physical overtraining: a placebo-controlled, randomized, double-blinded cross-over trial
The effect of multivitamin supplementation on mood and stress in healthy older men
The effects of multivitamin supplementation on mood and general well-being in healthy young adults. A laboratory and at-home mobile phone assessment
The Effects of Supplementation with a Vitamin and Mineral Complex with Guaran√° Prior to Fasted Exercise on Affect, Exertion, Cognitive Performance, and Substrate Metabolism: A Randomized Controlled Trial
Vitamin and mineral supplementation: effect on the running performance of trained athletes
Vitamin supplementation for 1 year improves mood
Vitamins and psychological functioning: a mobile phone assessment of the effects of a B vitamin complex, vitamin C and minerals on cognitive performance and subjective mood and energy
Vitamins, minerals and race performance in ultra-endurance runners--Deutschlandlauf 2006