The overall rating for l-citrulline is 1.8 out of 3 meaning there is some evidence that this supplement does some (not all) of what it claims. Using this supplement may lead to some improvements.

Table of Contents

  1. Simple Report
  2. Detailed Report
  3. Overall Effectiveness Rating
  4. Research Rating
  5. Products Containing L-Citrulline
  6. Claim Ratings
  7. Dosing
  8. References

L-Citrulline Simple Report

  • Supplement: L-Citrulline
  • Supplement Category: non-essential amino acids
  • Number of Products Containing L-Citrulline: 844
  • Effectiveness Rating: 1.8 out of 3
  • Research Rating: 20 (above 80 indicates sufficient research)
  • Number of Studies: 3
  • Number of Claims: 5
  • Effective Dosage Range: 2.4 grams per day

L-Citrulline Detailed Report

Overall Effectiveness Rating

The overall effectiveness rating for l-citrulline is 1.8 out of 3. This rating means the evidence is mixed on the supplement's ability to deliver positive results. While some of the research supports its use, other evidence does not. Using this supplement may lead to positive results. Note, this effectiveness rating is for l-citrulline as a whole; there are also individual ratings for the claims below.

Read more: What is the effectiveness rating?

Research Rating for L-Citrulline

There are 3 studies in the database on l-citrulline; the research rating is 20. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this research rating is for l-citrulline as a whole; there are also individual ratings for the claims below.

Read more: What is the research rating?

Products Containing L-Citrulline

Products Names Amount of L-Citrulline
Perform Xtreme 6g
Project Pump 2.5g
Predator Pro 7.5g
Wicked Amount not listed.
Key Pump 6g
Full list of all 844 products containing L-Citrulline.

Claim Ratings

The overall ratings above are an average of the individual claim ratings below. Individual claims may have higher or lower ratings compared to the supplement's overall rating. For example, some supplements may have excellent backing for one claim, but be completely useless for another. Click on a claim below for more information.

Performance Claims Effectiveness Rating Research Rating
improve cardiovascular endurance
improve cycling performance
improve muscular endurance
decrease fatigue
improve cycling sprint performance


The Supplement Database includes 2 studies on l-citrulline dosing. These studies indicate an effective dose is 2.4 grams per day. For a more detailed dosing analysis visit: Supplement Dosing for L-Citrulline.


Title of Study
l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans
Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study
The effect of l-citrulline and watermelon juice supplementation on anaerobic and aerobic exercise performance