Does histidine work?

Overall Effectiveness Rating for Histidine

The overall effectiveness rating for histidine is 3 out of 3. This rating means there is ample evidence that using histidine will lead to positive results.

Overall Confidence Rating for Histidine

There is one study in the database on histidine; the confidence rating is 20. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for histidine as a whole. There are also individual ratings for the claims below.

Products Containing Histidine

Products Containing Histidine
Amino Fire
Essential AmiN.O. Energy
Bloom Nutrition Recovery
Full list of all 32 products containing Histidine.

Individual Claims

The overall ratings above do no necessarily reflect each claim about histidine. Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Body Composition (weight, muscle, body fat) Claims Effectiveness Rating Confidence Rating
decrease body fat
increase weight loss

General Health Claims Effectiveness Rating Confidence Rating
improve insulin sensitivity


Title of Study
Histidine supplementation improves insulin resistance through suppressed inflammation in obese women with the metabolic syndrome: a randomised controlled trial