Eicosapentaenoic Acid (EPA)

Does eicosapentaenoic acid (epa) work?

Overall Effectiveness Rating for Eicosapentaenoic Acid (EPA)

The overall effectiveness rating for eicosapentaenoic acid (epa) is 1.4 out of 3. This rating means there is little to no evidence eicosapentaenoic acid (epa) does what it claims. Using this supplement will not lead to positive results.

Overall Confidence Rating for Eicosapentaenoic Acid (EPA)

There are 11 studies in the database on eicosapentaenoic acid (epa); the confidence rating is 46. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for eicosapentaenoic acid (epa) as a whole. There are also individual ratings for the claims below.

Products Containing Eicosapentaenoic Acid (EPA)

Products Containing Eicosapentaenoic Acid (EPA)
Omega Jym
Full list of all 1 products containing Eicosapentaenoic Acid (EPA).

Individual Claims

The overall ratings above do no necessarily reflect each claim about eicosapentaenoic acid (epa). Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Performance Claims Effectiveness Rating Confidence Rating
improve cardiovascular endurance
improve running performance

Cardiovascular Health Claims Effectiveness Rating Confidence Rating
lower LDL (bad) cholesterol levels
increase HDL (good) cholesterol levels
lower total cholesterol levels
lower triglyceride levels

Mental Health Claims Effectiveness Rating Confidence Rating
improve cognitive ability
improve memory

General Health Claims Effectiveness Rating Confidence Rating
improve insulin sensitivity
lower fasting glucose


Title of Study
Association between cognitive function and supplementation with omega-3 PUFAs and other nutrients in ≥ 75 years old patients: A randomized multicenter study
Circulating triacylglycerol and apoE levels in response to EPA and docosahexaenoic acid supplementation in adult human subjects
Dietary alpha-linolenic acid, EPA, and DHA have differential effects on LDL fatty acid composition but similar effects on serum lipid profiles in normolipidemic humans
Effect of 2-y n-3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: a randomized, double-blind, controlled trial
Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial
Effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on behavior and cognition in children with attention deficit/hyperactivity disorder (ADHD): a randomized placebo-controlled intervention trial
Effects of dietary alpha-linolenic acid, eicosapentaenoic acid or docosahexaenoic acid on parameters of glucose metabolism in healthy volunteers
Effects of iron and n-3 fatty acid supplementation, alone and in combination, on cognition in school children: a randomized, double-blind, placebo-controlled intervention in South Africa
Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial
Omega-3 fatty acid supplementation does not improve maximal aerobic power, anaerobic threshold and running performance in well-trained soccer players
The n-3 Polyunsaturated Fatty Acids Supplementation Improved the Cognitive Function in the Chinese Elderly with Mild Cognitive Impairment: A Double-Blind Randomized Controlled Trial