Does citicoline work?

Overall Effectiveness Rating for Citicoline

The overall effectiveness rating for citicoline is 2.8 out of 3. This rating means there is ample evidence that using citicoline will lead to positive results.

Overall Confidence Rating for Citicoline

There are 7 studies in the database on citicoline; the confidence rating is 80. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for citicoline as a whole. There are also individual ratings for the claims below.

Products Containing Citicoline

Products Containing Citicoline
Genius Burn
Genius BCAA
Professional Grade Gaming Formula
Full list of all 9 products containing Citicoline.

Individual Claims

The overall ratings above do no necessarily reflect each claim about citicoline. Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Cardiovascular Health Claims Effectiveness Rating Confidence Rating
lower blood pressure

Mental Health Claims Effectiveness Rating Confidence Rating
improve cognitive ability


Title of Study
Citicoline improves memory performance in elderly subjects
Citicoline improves verbal memory in aging
Citicoline Treatment Improves Measures of Impulsivity and Task Performance in Chronic Marijuana Smokers: A Pilot BOLD fMRI Study
Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer/'s disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion
Improvements in concentration, working memory and sustained attention following consumption of a natural citicoline-caffeine beverage
Improvements in quantitative EEG following consumption of a natural citicoline-enhanced beverage
The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males