Does betaine work?

Overall Effectiveness Rating for Betaine

The overall effectiveness rating for betaine is 1.6 out of 3. This rating means there is some evidence that using betaine may lead to positive results. This rating also means that some evidence does not back up all claims. Below you can find individual ratings for specific claims.

Overall Confidence Rating for Betaine

There are 7 studies in the database on betaine; the confidence rating is 46. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for betaine as a whole. There are also individual ratings for the claims below.

Products Containing Betaine

Products Containing Betaine
Alpha Amino
Full list of all 115 products containing Betaine.

Individual Claims

The overall ratings above do no necessarily reflect each claim about betaine. Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Body Composition (weight, muscle, body fat) Claims Effectiveness Rating Confidence Rating
decrease body fat
increase muscle mass

Performance Claims Effectiveness Rating Confidence Rating
improve muscular endurance
improve sports performance
decrease fatigue
increase strength

Recovery Claims Effectiveness Rating Confidence Rating
reduce muscle soreness


Title of Study
Creatine but not betaine supplementation increases muscle phosphorylcreatine content and strength performance
Effect of 15 days of betaine ingestion on concentric and eccentric force outputs during isokinetic exercise
Effect of betaine supplementation on power performance and fatigue
Effects of betaine on body composition, performance, and homocysteine thiolactone
Ergogenic effects of betaine supplementation on strength and power performance
The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial
The effects of chronic betaine supplementation on exercise performance, skeletal muscle oxygen saturation and associated biochemical parameters in resistance trained men