Alpha-Ketoisocaproic Acid

Does alpha-ketoisocaproic acid work?

Overall Effectiveness Rating for Alpha-Ketoisocaproic Acid

The overall effectiveness rating for alpha-ketoisocaproic acid is 1.4 out of 3. This rating means there is little to no evidence alpha-ketoisocaproic acid does what it claims. Using this supplement will not lead to positive results.

Overall Confidence Rating for Alpha-Ketoisocaproic Acid

There are 3 studies in the database on alpha-ketoisocaproic acid; the confidence rating is 23. A score above 80 means the effectiveness rating for this supplement is reliable. A score under 80 means there is insufficient evidence to ensure a reliable effectiveness rating. Note, this rating is for alpha-ketoisocaproic acid as a whole. There are also individual ratings for the claims below.

Individual Claims

The overall ratings above do no necessarily reflect each claim about alpha-ketoisocaproic acid. Individual claims can have higher or lower ratings. For example, some supplements may have a lot of backing for one claim, but be completely useless for another. Click on claims below for more information.

Performance Claims Effectiveness Rating Confidence Rating
improve high-intensity interval training (HIIT) performance
improve muscular endurance
improve sports performance

Recovery Claims Effectiveness Rating Confidence Rating
improve recovery
reduce muscle damage
reduce muscle soreness


Title of Study
Exercise-induced muscle damage is not attenuated by beta-hydroxy-beta-methylbutyrate and alpha-ketoisocaproic acid supplementation
Supplementation with beta-hydroxy-beta-methylbutyrate (HMB) and alpha-ketoisocaproic acid (KIC) reduces signs and symptoms of exercise-induced muscle damage in man
The effects of short-term alpha-ketoisocaproic acid supplementation on exercise performance: a randomized controlled trial